Center for Cancer Immunotherapy and Immunobiology

The 38th CCII Seminar “Leveraging metabolomics and biological networks for functional insights into microbiome” (Jianguo (Jeff) Xia)

Date, Time & Venue

Speaker

Dr. Jianguo (Jeff) Xia

Professor & Canada Research Chair
Department of Microbiology & Immunology
Faculty of Medicine and Health Sciences
McGill University

Abstract

Small molecule metabolites serve as critical mediators of host-microbiome interactions. High-resolution mass spectrometry-based global metabolomics generates comprehensive datasets that capture the complex landscape of host-microbiome co-metabolism. Proper integration of metabolomic and microbiome data represents a powerful approach for elucidating the biological mechanisms underlying host-microbiome interactions. In this talk, I will discuss our recent research developing integrated computational approaches, analytical methods, and C. elegans-based model systems to help understand microbiome functions and their dynamic interactions with host organisms.

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