Center for Cancer Immunotherapy and Immunobiology

Associate Professor Nariaki Asada (Incoming)
Junior PI

 

Education

  • 2018: Ph.D. (Medicine), Keio University
  • 2011: Kyoto University, Faculty of Medicine: Doctor of Medicine (M.D.)

Professional Experience

  • 2026~: Associate Professor, Center for Cancer Immunotherapy and Immunobiology (CCII)
  • 2019-2026: Postdoctoral Researcher, Division of Translational Immunology, III. Department of Medicine, University Medical Center Hamburg-Eppendorf (UKE), Germany
  • 2018-2019: Research Fellow, Molecular Endocrinology, National Center for Child Health and Development
  • 2015 -2018: Research Associate, Department of Pediatrics, Keio University School of Medicine
  • 2013-2015: Senior Resident in Pediatrics, Ota Memorial Hospital
  • 2011-2013: Junior Resident, Kyoto University Hospital

Research Focus

Honors & Awards

Selected Publications

Wang H, Engesser J, Khatri R, Schaub DP, Paust HJ, Sultana Z, Jauch-Speer SL, Peters A, Kaffke A, Bonn S, Huber TB, Mittrücker HW, Krebs CF, Panzer U, Asada N. Type I interferon drives T cell cytotoxicity by upregulation of interferon regulatory factor 7 in autoimmune kidney diseases in mice. Nat Commun. 2025;16(1):4686. (Corresponding author) DOI: 10.1038/s41467-025-59819-7

Asada N, Ginsberg P, Paust HJ, Song N, Riedel JH, Turner JE, Peters A, Kaffke A, Engesser J, Wang H, Zhao Y, Khatri R, Gild P, Dahlem R, Diercks BP, Das S, Ignatova Z, Huber TB, Prinz I, Gagliani N, Mittrücker HW, Krebs CF, Panzer U. The integrated stress response pathway controls cytokine production in tissue-resident memory CD4+ T cells. Nat Immunol. 2025;26(4):557–566. DOI: 10.1038/s41590-025-02105-x

Asada N, Krebs CF, Panzer U. Miniproteins may have a big impact: new therapeutics for autoimmune diseases and beyond. Signal Transduct Target Ther. 2024;9(1):298. DOI: 10.1038/s41392-024-02010-z

Engesser J, Wang H, Kapffer S, Kaffke A, Peters A, Paust HJ, Geissen M, Krebs CF, Panzer U, Asada N. S1PR1 mediates Th17 cell migration from the thymus to the skin in health and disease. Front Immunol. 2024;15:1473130. (Corresponding author) DOI: 10.3389/fimmu.2024.1473130

Ginsberg P, Panzer U, Asada N. Tissue-resident memory T cells in renal autoimmune diseases. Front Immunol. 2023:14:1111521. (Corresponding author) DOI: 10.3389/fimmu.2023.1111521

Asada N*, Ginsberg P*, Gagliani N, Mittrücker H, Panzer U. Tissue-resident memory T cells in the kidney. Semin Immunopathol. 2022 Nov;44(6):801-811. (* equally contributed) DOI: 10.1007/s00281-022-00927-7

Ohnishi T*, Asada N*, Furuichi M, Sekiguchi S, Awazu M, Hori N, I Kamimaki. A novel screening method for pediatric urinary tract infection using ordinary diapers. Sci Rep. 2020;10(1):19342. (* equally contributed. Asada N, corresponding author) DOI: 10.1038/s41598-020-76405-7

Asada N. Tubular immaturity causes erythropoietin-deficiency anemia of prematurity in preterm neonates. Sci Rep. 2018;8(1):4448. DOI: 10.1038/s41598-018-22791-y

Asada N, Tsukahara T, Furuhata M, Matsuda D, Noda S, Naganuma K, Hashiguchi A, Awazu M. Polycythemia, capillary rarefaction, and focal glomerulosclerosis in two adolescents born extremely low birth weight and premature. Pediatr Nephrol. 2017;32(7): 1275-1278. (Corresponding author) DOI: 10.1007/s00467-017-3654-z

Asada N, Kato I, Daifu T, Umeda K, Hiramatsu H, Okamoto T, Toguchida J, Yamawaki S, Yoshikawa K, Adachi S, Heike T, Watanabe K. Good Response to Chemotherapy Spares Irradiation for Extrarenal Rhabdoid Tumor Conferring Better Activities of Daily Living. J Pediatr Hematol Oncol. 2015;37(1):e57-9. DOI: 10.1097/MPH.0000000000000150

Asada N, Takase M, Nakamura J, Oguchi A, Asada M, Suzuki N, Yamamura K, Nagaoshi N, Shibata S, Tata Nageswara Rao, Hans Joerg Fehling, Fukatsu A, Minegishi N, Kita T, Kimura T, Okano H, Yamamoto M, and Yanagita M. Dysfunction of fibroblasts of extra- renal origin underlies renal fibrosis and renal anemia in mice. J Clin Invest. 2011;121(10): 3981-90. DOI: 10.1172/JCI57301

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